A Motor Relay on Ciliary Tracks
A powerful combination of two-colour imaging in vivo, Fourier-filtered kymography and simulations provides a high-resolution view of kinesin-2 transport dynamics in cilia. This study reveals heterotrimeric kinesin-II as an 'obstacle-course runner' and homodimeric OSM-3 (KIF17) as a 'long-distance runner', and elucidates the 'baton handoff' between these two kinesin-2 motors on the microtubule track.
MSU Digital Commons Citation
O'Hagan, Robert and Barr, Maureen M., "A Motor Relay on Ciliary Tracks" (2015). Department of Biology Faculty Scholarship and Creative Works. 28.