Natural Product Analogues: Towards a Blueprint for Analogue-Focused Synthesis
Journal / Book Title
Chemical Society Reviews
For the first time a general overview of approaches to the synthesis of natural product analogues is presented. This reflects a process of evolution of natural product synthesis which has accelerated in the years since the implementation of diversity-oriented synthesis, which has emerged in parallel with collective synthesis, diverted total synthesis and the preparation of truncated natural products optimised for biological activity. A method involving computational assessment for the validation of core-modified natural product analogues is discussed.
MSU Digital Commons Citation
Bebbington, Magnus, "Natural Product Analogues: Towards a Blueprint for Analogue-Focused Synthesis" (2017). Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works. 136.
Bebbington, M. W. (2017). Natural product analogues: towards a blueprint for analogue-focused synthesis. Chemical Society Reviews, 46(16), 5059-5109.