Title

The Effect of Pyrrolo[3,4-C]Carbazole Derivatives on Spinal Cord Chat Activity

Document Type

Article

Publication Date

6-8-1995

Abstract

Pyrrolo[3,4-c]carbazole derivatives were prepared as potential neurotrophic agents. The compounds were assayed for their ability to stimulate choline acetyltransferase (ChAT) activity in embryonic rat spinal cord cultures. These simplified K252a derivatives, although less potent and efficacious, have led to the identification of minimal structural requirements for K252a neurotrophic activity.

DOI

10.1016/0960-894X(95)00188-Y

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