Title

The Relationships Between Leptin and Measures of Fitness and Fatness Are Dependent Upon Obesity Status In Youth

Document Type

Article

Publication Date

1-1-2010

Abstract

The relationship between peak aerobic fitness (peakVO2) and plasma leptin was assessed in 25 normal (BMI < 85th %tile) and 25 overweight (BMI > 85th %tile) youth, ages 7-17 years. In the overall analysis peakVO2 was related to leptin when expressed in mL/kg/min (R 2 =.516, p <.0001), or as ml/kgFFM/min (R2 =.127, p =.01). The relationships between peakVO2 and leptin were no longer significant when percent bodyfat was added to the models. In subanalyses by weight groups, peakVO2: leptin relationships were not evident for normal weight, but remained for overweight youth. In conclusion the relationship between aerobic fitness and leptin in youth is dependent upon weight status.

DOI

10.1123/pes.22.2.195

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