How the timing of taking NSAIDs influence the progression of symptoms of musculoskeletal injuries
Presentation Type
Abstract
Faculty Advisor
Fredrick Gardin
Access Type
Event
Start Date
25-4-2025 9:00 AM
End Date
25-4-2025 10:00 AM
Description
There are various types of musculoskeletal injuries, including muscle contusions, strains, etc. that go through the healing process of inflammation, proliferation, and maturation. Many athletes use NSAIDs to reduce inflammation and pain. However, the short- and long-term effects of NSAIDs on the healing process are unclear. The purpose of this paper is to examine how the timing of taking NSAIDs influences the progression of symptoms of musculoskeletal injuries. A literature search was conducted in SPORTDiscus with Full Text on February 2025 using the terms “NSAID and muscle injury” and “NSAID and injury management”. The search limiters were full text, peer-reviewed, and English. The inclusion criteria included muscle injury, NSAID, and systematic/review articles. Five articles met the inclusion criteria. Overall, the benefits of NSAIDs for acute musculoskeletal injuries were inconsistent. The short-term benefits were reduction in pain, strength, and functional loss while the long-term use may inhibit satellite cell function for muscle healing. In addition, a suggestion for NSAID administration is 5-7 days after an acute injury to provide an analgesic effect rather than an anti-inflammatory one. Despite the many benefits of NSAIDs, there is a lack of studies on when NSAIDs should be administered without affecting the healing process. More research is needed to determine the best time to administer NSAIDs following an acute musculoskeletal injury. The current evidence suggests NSAIDs may provide short-term benefit for musculoskeletal injuries. However, the findings are unclear on how the timing of NSAIDs influences musculoskeletal injury symptoms. The SORT strength of recommendation is C.
How the timing of taking NSAIDs influence the progression of symptoms of musculoskeletal injuries
There are various types of musculoskeletal injuries, including muscle contusions, strains, etc. that go through the healing process of inflammation, proliferation, and maturation. Many athletes use NSAIDs to reduce inflammation and pain. However, the short- and long-term effects of NSAIDs on the healing process are unclear. The purpose of this paper is to examine how the timing of taking NSAIDs influences the progression of symptoms of musculoskeletal injuries. A literature search was conducted in SPORTDiscus with Full Text on February 2025 using the terms “NSAID and muscle injury” and “NSAID and injury management”. The search limiters were full text, peer-reviewed, and English. The inclusion criteria included muscle injury, NSAID, and systematic/review articles. Five articles met the inclusion criteria. Overall, the benefits of NSAIDs for acute musculoskeletal injuries were inconsistent. The short-term benefits were reduction in pain, strength, and functional loss while the long-term use may inhibit satellite cell function for muscle healing. In addition, a suggestion for NSAID administration is 5-7 days after an acute injury to provide an analgesic effect rather than an anti-inflammatory one. Despite the many benefits of NSAIDs, there is a lack of studies on when NSAIDs should be administered without affecting the healing process. More research is needed to determine the best time to administer NSAIDs following an acute musculoskeletal injury. The current evidence suggests NSAIDs may provide short-term benefit for musculoskeletal injuries. However, the findings are unclear on how the timing of NSAIDs influences musculoskeletal injury symptoms. The SORT strength of recommendation is C.
Comments
Poster presentation at the 2025 Student Research Symposium.