Water soluble fluorescent sensors for cation
Presentation Type
Abstract
Faculty Advisor
Saliya Desilva
Access Type
Event
Start Date
25-4-2025 9:00 AM
End Date
25-4-2025 9:59 AM
Description
Many Fluorescent Photoinduced Electron transfer (PET) sensors for cations are designed as fluorophore-spacer-receptor assemblies. These sensors are not fluorescent in the absence of a cation due to PET between the receptor and the fluorophore. Binding a cation in the receptor changes the oxidation potential of the receptor which quenches PET leading to a fluorescent signal. Since our sensors are large organic molecules they have low solubility in water and cation binding studies are carried out in methanol water mixtures. These sensors can be made water soluble by attaching a methyl imidazolium group that would allow us to use them in aqueous solutions. Several water soluble PET sensors with methyl imidazolium groups have been prepared on a small scale in our lab in the past. This project is focused on preparing larger amounts of these sensors for fluorescence studies.
Water soluble fluorescent sensors for cation
Many Fluorescent Photoinduced Electron transfer (PET) sensors for cations are designed as fluorophore-spacer-receptor assemblies. These sensors are not fluorescent in the absence of a cation due to PET between the receptor and the fluorophore. Binding a cation in the receptor changes the oxidation potential of the receptor which quenches PET leading to a fluorescent signal. Since our sensors are large organic molecules they have low solubility in water and cation binding studies are carried out in methanol water mixtures. These sensors can be made water soluble by attaching a methyl imidazolium group that would allow us to use them in aqueous solutions. Several water soluble PET sensors with methyl imidazolium groups have been prepared on a small scale in our lab in the past. This project is focused on preparing larger amounts of these sensors for fluorescence studies.
Comments
Poster presentation at the 2025 Student Research Symposium.