"Different Types of Backward Bifurcations Due to Density-Dependent Trea" by Baojun Song, Wen Du et al.
 

Different Types of Backward Bifurcations Due to Density-Dependent Treatments

Document Type

Article

Publication Date

10-1-2013

Journal / Book Title

Mathematical Biosciences & Engineering

Abstract

A set of deterministic SIS models with density-dependent treatments are studied to understand the disease dynamics when different treatment strategies are applied. Qualitative analyses are carried out in terms of general treatment functions. It has become customary that a backward bifurcation leads to bistable dynamics. However, this study finds that finds that bistability may not be an option at all; the disease-free equilibrium could be globally stable when there is a backward bifurcation. Furthermore, when a backward bifurcation occurs, the fashion of bistability could be the coexistence of either dual stable equilibria or the disease-free equilibrium and a stable limit cycle. We also extend the formula for mean infection period from density-independent treatments to density-dependent ones. Finally, the modeling results are applied to the transmission of gonorrhea in China, suggesting that these gonorrhea patients may not seek medical treatments in a timely manner.

Comments

This article is Open Access and distributed under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0)

DOI

10.3934/mbe.2013.10.1651

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