Progress in the Discovery and Development of Heat Shock Protein 90 (Hsp90) Inhibitors
Document Type
Article
Publication Date
11-13-2014
Abstract
The discovery and clinical development of heat shock protein 90 (Hsp90) inhibitors continue to progress. A number of Hsp90 inhibitors are in clinical trials, and preclinical discoveries of new chemotypes that bind to distinct regions in the protein as well as isoform selective compounds are active areas of research. This review will highlight progress in the field since 2010.
DOI
10.1021/jm500823a
Montclair State University Digital Commons Citation
Bhat, Rohit; Tummalapalli, Sreedhar R.; and Rotella, David, "Progress in the Discovery and Development of Heat Shock Protein 90 (Hsp90) Inhibitors" (2014). Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works. 321.
https://digitalcommons.montclair.edu/chem-biochem-facpubs/321