Ambiphilic Compounds: Synthesis and Structure of a Phosphane-Borane with a Flexible Diphenyl Ether Tether
The preparation of desired phosphane-borane 1 involves selective lithiation trapping of 2-bromo-2′-iododiphenyl ether 3 to give bromophosphane 4 followed by a second lithiation/electrophilic trapping to install the boron fragment. The structure of the new phosphane-borane was verified by single-crystal X-ray diffraction studies. A problematic intramolecular cyclization of lithiated intermediate 7 in THF was prevented by the use of toluene as the solvent. This result will also be of interest to chemists seeking to prepare related unsymmetrical diphosphanes.
MSU Digital Commons Citation
Bebbington, Magnus; Bouhadir, Ghenwa; and Bourissou, Didier, "Ambiphilic Compounds: Synthesis and Structure of a Phosphane-Borane with a Flexible Diphenyl Ether Tether" (2007). Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works. 376.