Silver Effect in Regiodivergent Gold-Catalyzed Hydroaminations

Authors

Marcos Veguillas, Heriot-Watt University
Georgina M. Rosair, Heriot-Watt University
Magnus Bebbington, Montclair State UniversityFollow
Ai Lan Lee, Heriot-Watt University

Document Type

Article

Publication Date

3-1-2019

Journal / Book Title

ACS Catalysis

Abstract

We report a silver-induced switching of regioselectivity in gold-catalyzed reactions, and we provide mechanistic evidence to suggest a true "silver effect": that is, one that is implicated in the catalytic process itself, via σ-gold π-silver acetylides. These results are of significance because they clearly show that the use of silver as halide abstractors in gold-catalyzed reactions may result in "silver effects" when terminal alkyne substrates are involved.

Comments

This article is Open Access and distributed under an ACS AuthorChoice license.

DOI

10.1021/acscatal.9b00249

Montclair State University Digital Commons Citation

Veguillas, Marcos; Rosair, Georgina M.; Bebbington, Magnus; and Lee, Ai Lan, "Silver Effect in Regiodivergent Gold-Catalyzed Hydroaminations" (2019). Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works. 496.
https://digitalcommons.montclair.edu/chem-biochem-facpubs/496

Published Citation

Veguillas, M., Rosair, G. M., Bebbington, M. W., & Lee, A. L. (2019). Silver effect in regiodivergent gold-catalyzed hydroaminations. ACS Catalysis, 9(3), 2552-2557.