Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation—Mapping for a Blood Pressure Response: A Case Series

Document Type

Article

Publication Date

9-1-2024

Journal / Book Title

Neurotrauma Reports

Abstract

Spinal cord transcutaneous stimulation (scTS) offers a promising approach to enhance cardiovascular regulation in individuals with a high-level spinal cord injury (SCI), addressing the challenges of unstable blood pressure (BP) and the accompanying hypo- and hypertensive events. While scTS offers flexibility in stimulation locations, it also leads to significant variability and lack of validation in stimulation sites utilized by studies. Our study presents findings from a case series involving eight individuals with chronic cervical SCI, examining the hemodynamic effects of scTS applied in different vertebral locations, spanning from high cervical to sacral regions. Stimulation of the lumbosacral vertebrae region (L1/2, S1/2, and also including T11/12) significantly elevated BP, unlike cervical or upper thoracic stimulation. The observed trend, which remained consistent across different participants, highlights the promising role of lumbosacral stimulation in neuromodulating BP.

Comments

The Author(s) 2024. Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

DOI

10.1089/neur.2024.0066

Journal ISSN / Book ISBN

85204896344 (Scopus)

Published Citation

Engel-Haber, E., Bheemreddy, A., Bayram, M. B., Ravi, M., Zhang, F., Su, H., Kirshblum, S., & Forrest, G. F. (2024). Neuromodulation in spinal cord injury using transcutaneous spinal stimulation—mapping for a blood pressure response: A case series. Neurotrauma Reports, 5(1), 845–856. https://doi.org/10.1089/neur.2024.0066

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