Date of Award
Master of Science (MS)
College of Science and Mathematics
Thesis Sponsor/Dissertation Chair/Project Chair
Ann Marie DiLorenzo
Tea is a highly consumed beverage with numerous health benefits, such as antioxidant and antiviral properties. The compounds within tea that are believed to be associated with these benefits are polyphenols. Black tea polyphenols are known as theaflavins, and in previous studies have exhibited inhibitory effects on influenza and human immunodeficiency virus 1. Herpes simplex virus -1 (HSV-1) is an extremely common virus and has the ability to cause recurrent infections. A vast majority of adults have been exposed to the virus and could be asymptomatic. The purpose of this study was to determine the lowest inhibitory concentration of black tea extracts on the herpes simplex virus -1. Utilizing plaque assays, DNA extraction, PCR, and gel electrophoresis, it was determined that viral inhibition occurs at a concentration of 0.1 ug/mL BTE.
Randall, Sadé Diahann, "Inhibition o f Herpes Simplex Virus-1 by Black Tea Extract" (2012). Theses, Dissertations and Culminating Projects. 964.