Long-Term Effects of Activity and of Calcium and Phosphorus Intake on Bones and Kidneys of Females Rats
Document Type
Article
Publication Date
12-1-1983
Journal / Book Title
The Journal of Nutrition
Abstract
Over a 22-week period, young female rats in conventional cages gained significantly more weight than rats housed with free access to running wheels. A trend toward increased bone density was indicated in runners. In a second test, young female rats were housed under the same conditions for 30 weeks, but the active group was then forced to run in a treadmill for 30 minutes, 5 times a week, over a 43-week period. During this time rats were fed either diets providing adequate Ca (0.5%) and adequate P (0.4%) or high P (1.2%), or low Ca (0.3%) and high P (1.2%). Running appeared to benefit long bone density but could not completely compensate for a high P or a low Ca, high P intake. A bone that received only indirect stress during exercise (atlas) was not significantly affected by running. However, a high P diet significantly decreased atlas bone density, while the negative effect of this diet on the density of long bones was at a lower level of significance. A low Ca, high P diet clearly decreased bone density in all bones investigated. Running had no effect on kidney mineralization, but either a high P or low Ca, high P diet greatly increased the concentration of these minerals in the kidney.
DOI
10.1093/jn/113.10.2011
MSU Digital Commons Citation
Bauer, Kathleen and Griminger, P., "Long-Term Effects of Activity and of Calcium and Phosphorus Intake on Bones and Kidneys of Females Rats" (1983). Department of Nutrition and Food Studies Scholarship and Creative Works. 68.
https://digitalcommons.montclair.edu/nutr-foodstudies-facpubs/68
