Document Type

Article

Publication Date

6-12-2015

Journal / Book Title

Computational Statistics

Abstract

A general framework for smooth regression of a functional response on one or multiple functional predictors is proposed. Using the mixed model representation of penalized regression expands the scope of function-on-function regression to many realistic scenarios. In particular, the approach can accommodate a densely or sparsely sampled functional response as well as multiple functional predictors that are observed on the same or different domains than the functional response, on a dense or sparse grid, and with or without noise. It also allows for seamless integration of continuous or categorical covariates and provides approximate confidence intervals as a by-product of the mixed model inference. The proposed methods are accompanied by easy to use and robust software implemented in the pffr function of the R package refund. Methodological developments are general, but were inspired by and applied to a diffusion tensor imaging brain tractography dataset.

DOI

10.1007/s00180-014-0548-4

Rights

NIH Public Access Author manuscript; available in PMC 2012 June 1. Published in final edited form as: J Comput Graph Stat. 2011 December 1; 20(4): 830–851. doi:10.1198/jcgs.2010.10007

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