A Motor Relay on Ciliary Tracks

Authors

Robert O'Hagan, Montclair State UniversityFollow
Maureen M. Barr, Rutgers - The State University of New Jersey, New BrunswickFollow

Document Type

Article

Publication Date

11-27-2015

Abstract

A powerful combination of two-colour imaging in vivo, Fourier-filtered kymography and simulations provides a high-resolution view of kinesin-2 transport dynamics in cilia. This study reveals heterotrimeric kinesin-II as an 'obstacle-course runner' and homodimeric OSM-3 (KIF17) as a 'long-distance runner', and elucidates the 'baton handoff' between these two kinesin-2 motors on the microtubule track.

DOI

10.1038/ncb3279

Montclair State University Digital Commons Citation

O'Hagan, Robert and Barr, Maureen M., "A Motor Relay on Ciliary Tracks" (2015). Department of Biology Faculty Scholarship and Creative Works. 28.
https://digitalcommons.montclair.edu/biology-facpubs/28