A Motor Relay on Ciliary Tracks
Document Type
Article
Publication Date
11-27-2015
Journal / Book Title
Nature Cell Biology
Abstract
A powerful combination of two-colour imaging in vivo, Fourier-filtered kymography and simulations provides a high-resolution view of kinesin-2 transport dynamics in cilia. This study reveals heterotrimeric kinesin-II as an 'obstacle-course runner' and homodimeric OSM-3 (KIF17) as a 'long-distance runner', and elucidates the 'baton handoff' between these two kinesin-2 motors on the microtubule track.
DOI
10.1038/ncb3279
Montclair State University Digital Commons Citation
O'Hagan, Robert and Barr, Maureen M., "A Motor Relay on Ciliary Tracks" (2015). Department of Biology Faculty Scholarship and Creative Works. 28.
https://digitalcommons.montclair.edu/biology-facpubs/28
Published Citation
O'Hagan, R., Barr, M. A motor relay on ciliary tracks. Nat Cell Biol 17, 1517–1519 (2015). https://doi.org/10.1038/ncb3279
