Why are Autism and the Fragile-X Syndrome Associated? Conceptual and Methodological Issues

Authors

Ira L. Cohen, New York State Institute for Basic Research in Developmental DisabilitiesFollow
Vicki Sudhalter, New York State Institute for Basic Research in Developmental DisabilitiesFollow
A. Pfadt, New York State Institute for Basic Research in Developmental Disabilities
Edmund C. Jenkins, New York State Institute for Basic Research in Developmental DisabilitiesFollow
W. Ted Brown, New York State Institute for Basic Research in Developmental DisabilitiesFollow
Peter Vietze, Montclair State UniversityFollow

Document Type

Review Article

Publication Date

2-20-1991

Abstract

Investigations of the association between autism and the fragile-X syndrome have yielded conflicting results with some studies indicating a strong correlation and others indicating no relation between the disorders. In this paper, we review the relevant research on this controversy and discuss the conceptual and methodological problems involved in such an inquiry. We conclude that autism and fragile X are associated and that this relation will prove fruitful in understanding the role of the X chromosome in a variety of behavior disorders and in unraveling various theoretical accounts on the etiology of autism.

MSU Digital Commons Citation

Cohen, Ira L.; Sudhalter, Vicki; Pfadt, A.; Jenkins, Edmund C.; Brown, W. Ted; and Vietze, Peter, "Why are Autism and the Fragile-X Syndrome Associated? Conceptual and Methodological Issues" (1991). Department of Psychology Faculty Scholarship and Creative Works. 587.
https://digitalcommons.montclair.edu/psychology-facpubs/587