Sokol Institute Publications

 
The Margaret and Herman Sokol Institute for Pharmaceutical Life Sciences was established by Montclair State University’s College of Science and Mathematics in 2007. It was created to rapidly advance the critical skills, approaches and research in developing solutions to global health issues. The Institute supports transdisciplinary research bringing CSAM faculty and students and academic and industry collaborators. Projects are in the areas of medicinal chemistry, pharmacology, biochemistry, natural products chemistry, molecular biology, computational sciences, and environmental toxicology. Research also takes place in emerging technologies such as biomaterials and nanotechnology.

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Submissions from 2026

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Potent, Selective Pyrrolopyrimidine PDE11A4 Inhibitors with Improved Pharmaceutical Properties, Shams ul Mahmood, Rama Krishna Boddu, Jeremy Eberhard, Charles S. Hoffman, John Gordon, Dennis Colussi, Wayne Childers, Elvis Amurrio, Marie Danaher, Michy P. Kelly, and David P. Rotella

Submissions from 2024

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Development of mass spectrometric glycan characterization tags using acid-base chemistry and/or free radical chemistry, Rayan Murtada, Shane Finn, and Jinshan Gao

Submissions from 2023

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Dynamics of diffusion, evaporation, and retention of organic solvents in paints by unilateral NMR and HR-MAS NMR spectroscopy, Valeria Di Tullio, Roberta Pigliapochi, Nicholas Zumbulyadis, Silvia A. Centeno, Jaclyn Catalano, Molly Wagner, and Cecil Dybowski

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Mechanistic Study into Free Radical-Activated Glycan Dissociations through Isotope-Labeled Cellobioses, Kimberly Fabijanczuk, Zaikuan Josh Yu, Rose M. Bakestani, Rayan Murtada, Nicholas Denton, Kaylee Gaspar, Tara Otegui, Jose Acosta, Hilkka I. Kenttämaa, Henk Eshuis, and Jinshan Gao

Submissions from 2022

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Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination, Angelo Cirinelli, Justin Wheelan, Christopher Grieg, and Carlos A. Molina

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Characterization of Competitive Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase**, Tyler Eck, Mariana Laureano de Souza, Melvin Delvillar, Kutub Ashraf, Rammohan R. Yadav Bheemanaboina, Ramappa Chakrasali, Tamara Kreiss, John J. Siekierka, David P. Rotella, Purnima Bhanot, and Nina M. Goodey

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Indole-3-Glycerol Phosphate Synthase From Mycobacterium tuberculosis: A Potential New Drug Target, Nikolas Esposito, David W. Konas, and Nina M. Goodey

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Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization, Natalie Hawryluk, Li Zhiru, Clotilde Carlow, Suzanne Gokool, Simon Townson, Tamara Kreiss, Agnieszka Chojnowski, Monika Prorok, John Siekierka, Alexandra Ehrens, Marianne Koschel, Nathaly Lhermitte-Vallarino, Coralie Martin, Achim Hoerauf, Geraldine Hernandez, and Stacie Canan

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A novel series of putative Brugia malayi histone demethylase inhibitors as potential anti-filarial drugs, Tamara Kreiss, Tyler Eck, Brittany Hart, Sreedhar Tummalapalli, David Rotella, and John Siekierka

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PolarClean & dimethyl isosorbide: green matches in formulating cathode slurry, Amrita Sarkar, Richard May, Zoren Valmonte, and Lauren E. Marbella

Submissions from 2021

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A sustainable approach to cathode delamination using a green solvent, Onurcan Buken, Kayla Mancini, and Amrita Sarkar

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Plasmodium falciparum cGMP-Dependent Protein Kinase – A Novel Chemotherapeutic Target, David Rotella, John Siekierka, and Purnima Bhanot

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Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase, Rammohan R. Yadav Bheemanaboina, Mariana Laureano de Souza, Mariana Lozano Gonzalez, Shams ul Mahmood, Tyler Eck, Tamara Kreiss, Samantha O. Aylor, Alison Roth, Patricia Lee, Brandon S. Pybus, Dennis J. Colussi, Wayne E. Childers, John Gordon, John J. Siekierka, Purnima Bhanot, and David P. Rotella

Submissions from 2020

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Mutational analysis confirms the presence of distal inhibitor-selectivity determining residues in B. stearothermophilus dihydrofolate reductase, Tyler Eck, Seema Patel, Thomas Candela, Katherine Leon H, Michael Little, Natalia E. Reis, Uththara Liyanagunawardana, Ueli Gubler, Cheryl A. Janson, Jaclyn Catalano, and Nina M. Goodey

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Voltammetric pH Measurements in Unadulterated Foodstuffs, Urine, and Serum with 3D-Printed Graphene/Poly(Lactic Acid) Electrodes, Fakher M. Rabboh and Glen D. O'Neil

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Light-Addressable Electrochemical Sensing with Electrodeposited n-Silicon/Gold Nanoparticle Schottky Junctions, Irina M. Terrero Rodríguez, Alexandra J. Borrill, Katherine J. Schaffer, Jocelyn B. Hernandez, and Glen D. O'Neil

Submissions from 2019

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Discovery of isoxazolyl-based inhibitors of Plasmodium falciparum cGMP-dependent protein kinase, Shams ul Mahmood, Huimin Cheng, Sreedhar R. Tummalapalli, Ramappa Chakrasali, Rammohan R. Yadav Bheemanaboina, Tamara Kreiss, Agnieszka Chojnowski, Tyler Eck, John J. Siekierka, and David P. Rotella

Submissions from 2016

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The transcriptional repressor ICER binds to multiple loci throughout the genome, Carlos A. Molina and Luis C. Muñiz